Seneca, SC Homes & Real Estate for Sale

Page 1 of 18
356 listings
506 Horseshoe Drive, Seneca, SC 29678New listing icon New - 23 hours ago
Single-Family Home For Sale

$699,900

  • 5 bed |
  • 4 bath |
  • 1.18 acre lot
506 Horseshoe Drive Seneca, SC 29678

#20290381 - Clardy Real Estate

28.32 Acres Clemson Boulevard With Sewer, Seneca, SC 29678New listing icon New - 23 hours ago
Land For Sale

$1,416,000

  • 28.5 acre lot
28.32 Acres Clemson Boulevard With Sewer Seneca, SC 29678

#20289835 - Re/Max Realty Professionals

409 Tiger Tail Road, Seneca, SC 29678New listing icon New - 23 hours ago
Single-Family Home For Sale

$299,900

  • 3 bed |
  • 2 bath |
  • 1,800 sqft |
  • 1.73 acre lot
409 Tiger Tail Road Seneca, SC 29678

#20290323 - Keller Williams Easley/Powd

209 Summerall Lane, Seneca, SC 29678New listing icon New - 23 hours ago
Single-Family Home For Sale

$514,990

  • 5 bed |
  • 4 bath |
  • 3,898 sqft
209 Summerall Lane Seneca, SC 29678

#20290330 - DRB Group South Carolina, LLC

213 Summerall Lane, Seneca, SC 29678New listing icon New - 23 hours ago
Single-Family Home For Sale

$456,990

  • 4 bed |
  • 4 bath |
  • 2,608 sqft
213 Summerall Lane Seneca, SC 29678

#20290329 - DRB Group South Carolina, LLC

Lot 127 Longwood Drive, Seneca, SC 29672New listing icon New - 23 hours ago
Land For Sale

$228,000

  • 1.59 acre lot
Lot 127 Longwood Drive Seneca, SC 29672

#20290362 - Lake Keowee Real Estate

405 Keith Lane, Seneca, SC 29678New listing icon New - 1 day ago
Single-Family Home For Sale

$234,900

  • 3 bed |
  • 2 bath |
  • 1,260 sqft |
  • 0.38 acre lot
405 Keith Lane Seneca, SC 29678

#20290363 - Brackin Ventures Realty

111 Madison Pointe Drive, Seneca, SC 29678New listing icon New - 1 day ago
Single-Family Home For Sale

$349,500

  • 4 bed |
  • 2 bath |
  • 1,808 sqft |
  • 10,019 sqft lot
111 Madison Pointe Drive Seneca, SC 29678

#20290115 - Allen Tate - Lake Keowee Seneca

506 Quincy Road, Seneca, SC 29678New listing icon New - 1 day ago
Single-Family Home For Sale

$337,990

  • 3 bed |
  • 2 bath |
  • 1,920 sqft |
  • 0.45 acre lot
506 Quincy Road Seneca, SC 29678

#20290238 - Monaghan Company Real Estate

100 Red Cardinal Road, Seneca, SC 29672New listing icon New - 1 day ago
Rental Available

$2,400 /mo

  • 3 bed |
  • 3 bath |
  • 0.66 acre lot
100 Red Cardinal Road Seneca, SC 29672

#20290339 - ERA Kennedy Group Seneca

00 N Perkins Creek Road, Seneca, SC 29678New listing icon New - 1 day ago
Land For Sale

$104,999

  • 4.65 acre lot
00 N Perkins Creek Road Seneca, SC 29678

#20290288 - Clardy Real Estate - W Union

42 Sirrine Street, Seneca, SC 29678New listing icon New - 1 day ago
Single-Family Home For Sale

$179,000

  • 3 bed |
  • 2 bath |
  • 1,235 sqft |
  • 6,970 sqft lot
42 Sirrine Street Seneca, SC 29678

#20290265 - Clardy Real Estate - Lake Keowee

308 Treetops Drive, Seneca, SC 29672New listing icon New - 1 day ago
Single-Family Home For Sale

$2,850,000

  • 4 bed |
  • 7 bath |
  • 6,445 sqft |
  • 1.49 acre lot
308 Treetops Drive Seneca, SC 29672

#20290137 - Top Guns Realty

508 Broad Creek Court, Seneca, SC 29678New listing icon New - 1 day ago
Single-Family Home For Sale

$404,928

  • 4 bed |
  • 3 bath |
  • 0.34 acre lot
508 Broad Creek Court Seneca, SC 29678

#20290077 - The Les Walden Team

505 Dalton Road, Seneca, SC 29678New listing icon New - 2 days ago
Single-Family Home For Sale

$549,900

  • 3 bed |
  • 3 bath |
  • 2,400 sqft |
  • 1.5 acre lot
505 Dalton Road Seneca, SC 29678

#20290260 - Clardy Real Estate

504 Bolick Street, Seneca, SC 29672New listing icon New - 2 days ago
Single-Family Home For Sale

$250,000

  • 4 bed |
  • 2 bath |
  • 1,425 sqft |
  • 0.27 acre lot
504 Bolick Street Seneca, SC 29672

#20290282 - Clardy Real Estate - W Union

340 Earls Mill Road, Seneca, SC 29678New listing icon New - 2 days ago
Manufactured Home For Sale

$179,000

  • 3 bed |
  • 2 bath |
  • 1,216 sqft |
  • 0.91 acre lot
340 Earls Mill Road Seneca, SC 29678

#20290169 - Talan Properties LLC

13500 Clemson Boulevard 2207,2209,2221,2219, Seneca, SC 29678New listing icon New - 2 days ago
Condominium For Sale

$990,000

  • 1 bed |
  • 1 bath
13500 Clemson Boulevard 2207,2209,2221,2219 Seneca, SC 29678

#20290251 - Lakeside Lodge - Clemson

8006 Keowee School Road, Seneca, SC 29672New listing icon New - 3 days ago
Land For Sale

$625,000

  • 24.7 acre lot
8006 Keowee School Road Seneca, SC 29672

#20290217 - Real Local/Real Broker, LLC (Seneca)

405 Oakmont Valley Trail, Seneca, SC 29678New listing icon New - 3 days ago
Rental Available

$2,050 /mo

  • 4 bed |
  • 3 bath
405 Oakmont Valley Trail Seneca, SC 29678

#20290218 - Carolina Home Real Estate Inc.

Presented by Darren Sweet - Veterans United Realty

Veterans United Homefront
© 2025 Western Upstate Multiple Listing Service, Inc. All rights reserved. The data relating to real estate for sale on this Web site comes in part from the Broker Reciprocity Program of the Western Upstate Association of REALTORS®, Inc. and the Western Upstate Multiple Listing Service, Inc. IDX information is provided exclusively for consumers’ personal, non-commercial use, that it may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing.

This information is deemed reliable, but not guaranteed. Neither the Western Upstate Association of REALTORS®, Inc. or Western Upstate Multiple Listing Service of South Carolina, Inc., nor the listing broker, nor their agents or subagents are responsible for the accuracy of this information. The buyer is responsible for verifying all information. Data displayed may be a portion of, and not a complete set of all listings published in the MLS.

For questions call 1-833-252-8030

Copyright © 2025 Veterans United Realty and Did You Serve, LLC. Homefront.com is NOT affiliated with any government agencies, including the VA. Homefront.com is a service of Did You Serve, LLC. Veterans United and the Veterans United House logo are registered trademarks of Mortgage Research Center, LLC, used under license agreement. Terms of Use.